Posted: November 21, 2010
A new study has reported that an anthocyanin-rich extract from black
rice inhibits breast cancer cell growth in cell cultures and when fed
to mice bearing tumors grown from human breast cancer cell lines. Anthocyanins are polyphenol pigments that are widely present in red and purple fruits, vegetables and grains, including the following:
The
study was designed to investigate the anticancer activities of the
black rice extract on a variety of breast cancer cell lines, including hormone receptor positive MCF-7 (ER+, HER2/neu-), triple negative MDA-MB-231 (ER-, HER2/neu-), and HER2-overexpressing
MDA-MB-453 (ER-, HER2/neu+) cells. Anthocyanin-rich black rice extract
was found to reduce the viability of all of the breast cancer cell
lines. The extract also was shown to induce apoptosis (i.e., it
activated internal cell programs for cell suicide) in the
HER2-overexpressing cells. In addition, feeding black rice extract to
mice with implanted triple negative cells was found to significantly
inhibit tumor growth and angiogenesis
(new blood vessel formation). The authors conclude that black rice
extract appears to have anticancer effects against human breast cancer
cells by inducing apoptosis and suppressing angiogenesis.
http://foodforbreastcancer.com/news/black-rice-compound-induces-breast-cancer-cell-death-and-and-suppresses-angiogenesis
http://foodforbreastcancer.com/news/black-rice-compound-induces-breast-cancer-cell-death-and-and-suppresses-angiogenesis
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